Domains of expertise : images analysis |
QUANTITATIVE RADIOLUMINOGRAPHY APPLIED TO TISSUE DISTRIBUTION BY IMAGE ANALYSIS
 Study of the distribution of a radiolabelled test item, quantitation by image analysis within tissues and body fluids of different species (from mouse, mini-pig to monkey, QRLG)
Application to :
 placental transfer (rat, mouse),
blood-brain barrier transfer (rat, mouse, monkey),
transcutaneous passage, localisation into the different skin appendages (rat, dog, pig, human).
Standard calibration curve |
Monkey brain
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Chicken
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Use of two Leica cryomacrocut.
Quick and accurate quantitative data for drug screening using photostimulable screens exposed to freeze-dried histological sections of animals (2-10 day exposure time) Large scale over linear/log decades.
Radioluminograms and results stored on hard disk and on recordable CD-ROMs. |
Dog skin |
Easy data transfer of results/images by email and with CD-recordable. |
Bio-Imaging Analyser |
Contact : Paula FERREIRA
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France - Phone : +(33) 2 38 76 20 60 - Fax : +(33) 2 38 76 20 59 - Contact E-mail